Yes, it's typical of most knock-off equipped race cars. Every sprint car rear axle has the left hand threads on the right side of the car. The difference between the knock off nut and the spindle thread in your example is the knock off nut is spinning with the wheel, while the spindle nut is fixed to the spindle or rear end housing. As far as the OP's question goes, the safety wire is not necessary. IMO, it's mostly for show...in a racing application it would defeat the purpose of the knock-offs...which is fast pit stops.