Excuse my lack of knowledge... Say a body panel is 18 gauge, can you use 16 gauge to patch it or is that asking for trouble?
I find most vintage cars to be around 19 gauge, I use 18 for patches on them. 16 is pretty heavy for body repairs unless for structural.
Use 18 gauge !!! You will be much happier with your welds. Mis-matched gauge will result in uneven heating of your metal and can produce some "Funky Welds". When you metal finish your welds, you will find that mis-matched gauge will be a "PITA" to hammer and dolly............. Jeff